SCHEMBL24390191

SCHEMBL24390191

CCC(CC)COC(=O)/C(C#N)=C/C=C1\Sc2ccccc2N1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FNTA P49354 7/20 0.49
▸ FNTB P49356 7/20 0.49
▸ MAPT P10636 11/20 0.43
▸ MEN1 O00255 10/20 0.43
▸ KMT2A Q03164 10/20 0.43
▸ ALDH1A1 P00352 8/20 0.43
▸ L3MBTL1 Q9Y468 4/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ MAPK1 P28482 1/20 0.43
▸ RAB9A P51151 8/20 0.43
▸ NPC1 O15118 6/20 0.43
▸ NPSR1 Q6W5P4 3/20 0.43
▸ KDM4E B2RXH2 3/20 0.43
▸ USP2 O75604 6/20 0.43
▸ SMN1; SMN2 Q16637 6/20 0.43
▸ CRHBP P24387 3/20 0.43
▸ CRHR2 Q13324 3/20 0.43
▸ LMNA P02545 2/20 0.43
▸ HPGD P15428 1/20 0.42
▸ GAA P10253 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390194 0.89 MAPT (0.56) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL24390187 0.89 FNTA (0.60) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL24390176 0.78 MAPT (0.43) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL24390185 0.77 MAPT (0.70) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL10036074 0.74 MAPT (0.61) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL13889560 0.73 MAPT (0.52) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL24390195 0.71 MAPT (0.47) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL14582149 0.71 MEN1 (0.46) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL14582207 0.71 MEN1 (0.46) FNTAFNTBMAPTMEN1KMT2A
SCHEMBL24390232 0.71 MAPT (0.78) FNTAFNTBMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE FUJIFILM CORPORATION (JP) 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220137260-A1 POLYMERIZABLE COMPOSITION, COMPOUND, POLYMER, RESIN COMPOSITION, ULTRAVIOLET CUT FILM, AND LAMINATE RER1, C5, RAD51 FNTA 3099/4885FNTB 3571/4885MAPT 1441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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