Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 8/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24392619 | 0.81 | EGLN2 (0.35) | ALDH1A1EGLN2MAPK1TSHRALOX15 | |
| SCHEMBL24392620 | 0.81 | ALDH1A1 (0.33) | ALDH1A1EGLN2MAPK1TSHRALOX15 | |
| SCHEMBL24393212 | 0.81 | ALDH1A1 (0.35) | ALDH1A1EGLN2TSHRKDM4EPKM | |
| SCHEMBL24393051 | 0.80 | ALDH1A1 (0.46) | ALDH1A1EGLN2MAPK1TSHRKDM4E | |
| SCHEMBL24391780 | 0.79 | ACVRL1 (0.33) | ALDH1A1EGLN2MAPK1TSHRALOX15 | |
| SCHEMBL24393158 | 0.77 | ALDH1A1 (0.35) | ALDH1A1MAPK1KDM4EPKMENPP1 | |
| SCHEMBL24393360 | 0.76 | ALDH1A1 (0.34) | ALDH1A1EGLN2MAPK1KDM4EPKM | |
| SCHEMBL24393358 | 0.73 | EGLN2 (0.38) | EGLN2 | |
| SCHEMBL24197718 | 0.67 | EGFR (0.35) | ALDH1A1EGLN2MAPK1TSHRALOX15 | |
| SCHEMBL15147291 | 0.65 | ALDH1A1 (0.38) | ALDH1A1EGLN2MAPK1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091048-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |