Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24392470 | 0.83 | ALDH1A1 (0.36) | LMNAADORA2AADORA1YTHDC1RECQL | |
| SCHEMBL24392652 | 0.82 | ADORA2A (0.32) | LMNAADORA2AADORA1YTHDC1 | |
| SCHEMBL29589444 | 0.72 | PARP1 (0.44) | ADORA1 | |
| SCHEMBL24392467 | 0.72 | PARP1 (0.44) | ADORA1 | |
| SCHEMBL12352344 | 0.71 | LMNA (0.42) | LMNAADORA2AADORA1YTHDC1RECQL | |
| SCHEMBL10256984 | 0.68 | LMNA (0.34) | LMNA | |
| SCHEMBL29306587 | 0.68 | EGFR (0.32) | — | |
| SCHEMBL24463147 | 0.67 | LMNA (0.35) | LMNAADORA2AADORA1RECQL | |
| SCHEMBL29302056 | 0.67 | LMNA (0.33) | LMNA | |
| SCHEMBL10147304 | 0.66 | LMNA (0.46) | LMNAADORA2AADORA1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091048-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |