Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24391801 | 0.80 | PIK3CD (0.33) | MBOAT4KDM4EALDH1A1HPGDRIPK1 | |
| SCHEMBL24393212 | 0.78 | ALDH1A1 (0.35) | KDM4EALDH1A1HTT | |
| SCHEMBL24393151 | 0.74 | HTT (0.38) | ALDH1A1HTTPDE2A | |
| SCHEMBL24393330 | 0.72 | ALDH1A1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL23761189 | 0.68 | PIK3CD (0.45) | MBOAT4RIPK1PIK3CD | |
| SCHEMBL24392052 | 0.67 | ALDH1A1 (0.35) | KDM4EALDH1A1HTT | |
| SCHEMBL24393049 | 0.67 | ALDH1A1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL24393136 | 0.67 | IRAK4 (0.35) | MBOAT4KDM4EALDH1A1 | |
| SCHEMBL24393160 | 0.65 | ALDH1A1 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL24392666 | 0.65 | ALDH1A1 (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022091048-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 (ENPP1) INHIBITORS AND USES THEREOF | INTEGRAL BIOSCIENCES PRIVATE LIMITED (IN) | 2022-05-05 | — | — | WO | disclosed |