SCHEMBL24394232

SCHEMBL24394232

CC1(C)OB(c2ccc(-c3cc(F)c(N)c(F)c3)cc2)OC1(C)C

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 13/20 0.65
LPL P06858 12/20 0.65
CA1 P00915 4/20 0.42
CA2 P00918 4/20 0.42
CA9 Q16790 4/20 0.42
CA12 O43570 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
F11 P03951 2/20 0.41
F2 P00734 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
SNCA P37840 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26371403 0.87 LIPG (0.57) LIPGLPLCA1CA2CA9
SCHEMBL26371387 0.83 LPL (0.47) LIPGLPLCA1CA2CA9
SCHEMBL59540 0.83 LPL (0.47) LIPGLPLCA1CA2CA9
SCHEMBL12681706 0.82 LIPG (0.74) LIPGLPLCA1CA2CA9
SCHEMBL24608995 0.80 LIPG (0.83) LIPGLPLCA1CA2CA9
SCHEMBL2707320 0.80 LIPG (0.83) LIPGLPLCA1CA2CA9
SCHEMBL792244 0.79 LIPG (1.00) LIPGLPLCA1CA2CA9
SCHEMBL59080 0.76 LPL (0.53) LIPGLPLCA1CA2CA9
SCHEMBL18270358 0.76 LIPG (0.89) LIPGLPLCA1CA2CA9
SCHEMBL18270355 0.76 LIPG (0.89) LIPGLPLCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230392075-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2023-12-07 US disclosed
EP-4237509-A1 AROMATIC ISOTHIOCYANATES Merck Patent GmbH (DE) 2023-09-06 EP disclosed
CN-116490591-A Aromatic isothiocyanates 默克专利股份有限公司 2023-07-25 CN disclosed
WO-2022090109-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2022-05-05 WO disclosed
WO-2022090109-A1 AROMATIC ISOTHIOCYANATES MERCK PATENT GMBH (DE) 2022-05-05 WO disclosed