SCHEMBL243947

SCHEMBL243947

CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
CHRM5 P08912 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26430616 0.79
SCHEMBL11270523 0.78 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL23035533 0.78 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29438529 0.78 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL231141 0.78 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
Ammonia Solution, Strong SCHEMBL27574121 0.76 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL10683639 0.74 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL8315504 0.73
SCHEMBL19339992 0.71 CHRM2 (0.32) CHRM2CHRM4CHRM5CHRM1CHRM3
Methylene Chloride SCHEMBL11402933 0.71 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748846-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY TAKING TRANSIENTLY PROTECTED AMINO ACID AS AMMONIA COMPONENT GUANGZHOU MEDICAL UNIVERSITY (CN) 2026-05-27 EP claimed
EP-4703369-A1 METHOD FOR SYNTHESIZING AMIDE AND/OR POLYPEPTIDE BY USING TEMPORARILY PROTECTED AMINO ACIDS AS AMINE COMPONENTS GUANGZHOU MEDICAL UNIVERSITY (CN) 2026-03-04 EP claimed
US-20260001907-A1 Method for Synthesizing Amide and/or Polypeptide Using Transient Protected Amino Acid as Ammonia Component UNIV GUANGZHOU MEDICAL (CN) 2026-01-01 US claimed
US-20260001906-A1 Method for Synthesizing Amide and/or Polypeptide Using Temporary Protected Amino Acid as Ammonia Component UNIV GUANGZHOU MEDICAL (CN) 2026-01-01 US claimed
EP-4649314-A2 POLYOL SWEETENERS AND CARDIOVASCULAR AND THROMBOTIC EVENT RISK The Cleveland Clinic Foundation (US) 2025-11-19 EP claimed
WO-2025104679-A1 PROCESSES FOR MAKING INTERMEDIATES FOR ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICANCER ACTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-05-22 WO claimed
CN-119846104-A Detection method for multiple polycyclic aromatic hydrocarbon metabolites in urine 中国疾病预防控制中心环境与健康相关产品安全所 2025-04-18 CN claimed
CN-119725753-A Electrolyte containing silane additive and lithium ion battery 惠州亿纬锂能股份有限公司 2025-03-28 CN claimed
CN-115825301-B Method for measuring impurity content in 2-bromobutyric acid by gas derivatization chromatography 江苏宝众宝达药业股份有限公司 2025-03-14 CN claimed
CN-119371478-A Method for synthesizing amide and/or polypeptide by taking transient protection amino acid as ammonia component 广州医科大学 2025-01-28 CN claimed
US-5800979-A Gas chromatography/mass spectrometric determination of folic acid coenzymes KOLHOUSE J FRED (US) 1998-09-01 US claimed
US-5559038-A Gas chromatography/mass spectrometry determination of oxidized sulfhydryl amino acids THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 1996-09-24 US claimed
EP-0486118-B1 Method for detecting cobalamin and folic acid deficiency COMPETITIVE TECH INC (US) 1996-06-12 EP claimed
US-5438017-A Assays for sulfhydryl amino acids and methylmalonic acid and their application to diagnosis of cobalamin deficiency THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) 1995-08-01 US claimed
US-5374560-A Method for screening and distinguishing between cobalamin and folic acid deficiency based on assay for cystathionine and 2-methylcitric acid THE UNIVERSITY OF COLORADO, INC. (US) 1994-12-20 US claimed
EP-0269352-B1 ASSAY FOR SULFHYDRYL AMINO ACIDS AND METHODS FOR DETECTING AND DISTINGUISHING COBALAMIN AND FOLIC ACID DEFICIENCY UNIVERSITY PATENTS, INC. (US) 1993-03-17 EP claimed
WO-1993001496-A1 METHOD FOR DETECTING AND DISTINGUISHING BETWEEN COBALAMIN AND FOLIC ACID DEFICIENCY BASED ON AMINO ACID ASSAY THE UNIVERSITY OF COLORADO FOUNDATION, INC. (US) 1993-01-21 WO claimed
EP-0486118-A1 Method for detecting cobalamin and folic acid deficiency COMPETITIVE TECHNOLOGIES INC. (US) 1992-05-20 EP claimed
US-4940658-A Assay for sulfhydryl amino acids and methods for detecting and distinguishing cobalamin and folic acid deficency UNIVERSITY PATENTS, INC. (US) 1990-07-10 US claimed
EP-0269352-A2 Assay for sulfhydryl amino acids and methods for detecting and distinguishing cobalamin and folic acid deficiency UNIVERSITY PATENTS, INC. (US) 1988-06-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001907-A1 Method for Synthesizing Amide and/or Polypeptide Using Transient Protected Amino Acid as Ammonia Component BCAT1, BCAT2, VIP CHRM2 3880/4885CHRM4 4001/4885CHRM5 3845/4885
US-20260001906-A1 Method for Synthesizing Amide and/or Polypeptide Using Temporary Protected Amino Acid as Ammonia Component BCAT1, BCAT2, PTMS CHRM2 3255/4885CHRM4 3690/4885CHRM5 3967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.