Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 8/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6502286 | 0.90 | HDAC1 (0.39) | USP30GPR119RORC | |
| SCHEMBL2434897 | 0.89 | USP30 (0.38) | USP30GPR119RORCCHRM2CHRM3 | |
| SCHEMBL2059484 | 0.88 | HSD11B1 (0.40) | USP30 | |
| SCHEMBL704571 | 0.82 | ABCB1 (0.41) | USP30GPR119RORCCHRM3ABCB1 | |
| SCHEMBL27223224 | 0.82 | ABCB1 (0.41) | USP30GPR119RORCCHRM3ABCB1 | |
| SCHEMBL23043429 | 0.82 | ABCB1 (0.41) | USP30GPR119RORCCHRM3ABCB1 | |
| SCHEMBL1260709 | 0.81 | HSD11B1 (0.35) | USP30GPR119KDM1ARORC | |
| SCHEMBL1083425 | 0.81 | GPR119 (0.34) | USP30GPR119RORC | |
| SCHEMBL1072985 | 0.81 | GPR119 (0.34) | USP30GPR119RORC | |
| SCHEMBL18321103 | 0.80 | NR1H2 (0.36) | GPR119RORCCHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |