SCHEMBL24398609

SCHEMBL24398609

C=C/C(=C\c1c(C)n(-c2ccccc2)c2ccccc12)c1ccc2c(c1)c1ncccc1n2-c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RORC P51449 2/20 0.37
▸ GAA P10253 1/20 0.33
▸ GFER P55789 1/20 0.33
▸ KDM4E B2RXH2 4/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ ATM Q13315 1/20 0.33
▸ HPGD P15428 3/20 0.32
▸ HSD17B10 Q99714 3/20 0.32
▸ ALDH1A1 P00352 3/20 0.32
▸ HTT P42858 3/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ CASP1 P29466 1/20 0.32
▸ CASP7 P55210 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ REN P00797 6/20 0.32
▸ MAPT P10636 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22408862 0.88 KDM4E (0.42) RORCGAAGFERKDM4EL3MBTL1
SCHEMBL25024928 0.83 KDM4E (0.38) RORCGAAGFERKDM4EL3MBTL1
SCHEMBL18542855 0.82 RORC (0.38) RORCGAAGFERKDM4EL3MBTL1
SCHEMBL25737373 0.80 PTGER4 (0.35) RORCGAAGFERKDM4EL3MBTL1
SCHEMBL24631962 0.77 RORC (0.34) RORCGAAGFERKDM4EL3MBTL1
SCHEMBL23812751 0.77 RORC (0.38) RORCGAAGFERKDM4EL3MBTL1
SCHEMBL20683182 0.76 RORC (0.32) RORCGAAGFERKDM4EL3MBTL1
SCHEMBL22627800 0.76 KDM4E (0.32) RORCKDM4EL3MBTL1ATMHSD17B10
SCHEMBL22326663 0.74 KDM4E (0.32) RORCGAAKDM4EL3MBTL1ATM
SCHEMBL22417767 0.74 MAPT (0.31) HPGDHSD17B10MEN1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220135605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135605-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, TRPA1 RORC 2466/4885GAA 1864/4885GFER 1316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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