⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25712726 | 0.83 | TSHR (0.31) | — | |
| SCHEMBL24399541 | 0.78 | TSHR (0.31) | — | |
| SCHEMBL24794964 | 0.75 | — | — | |
| SCHEMBL25712730 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL5222623 | 0.70 | — | — | |
| SCHEMBL8728883 | 0.69 | TSHR (0.39) | — | |
| Methyl Alcohol SCHEMBL28414164 | 0.68 | ALDH1A1 (0.38) | — | |
| SCHEMBL24856 | 0.67 | — | — | |
| SCHEMBL14771062 | 0.67 | CES2 (0.47) | — | |
| SCHEMBL2952521 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12031179-B2 | Methods and compositions for reducing nucleotide impurities | Singular Genomics Systems, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230399692-A1 | NUCLEIC ACID DELIVERY SCAFFOLDS | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-12-14 | — | — | US | disclosed |
| WO-2023212369-A1 | NUCLEOTIDE CYCLIC CLEAVABLE MOIETIES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-11-02 | — | — | WO | disclosed |
| US-11795505-B2 | Nucleic acid delivery scaffolds | Singular Genomics Systems, Inc. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20230287491-A1 | NUCLEIC ACID DELIVERY SCAFFOLDS | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-09-14 | — | — | US | disclosed |
| WO-2023172665-A2 | NUCLEIC ACID DELIVERY SCAFFOLDS | Singular Genomics Systems, Inc. (US) | 2023-09-14 | — | — | WO | disclosed |
| US-20230265505-A1 | METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-24 | — | — | US | disclosed |
| US-20230242571-A1 | SILICON CONTAINING MODIFIED NUCLEOTIDE ANALOGS | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-03 | — | — | US | disclosed |
| WO-2023107673-A2 | CLEAVABLE DISULFIDE LINKERS AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20230119408-A1 | NUCLEOTIDE ANALOGS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-04-20 | — | — | US | disclosed |
| WO-2022271970-A1 | METHODS AND COMPOSITIONS USEFUL FOR NUCLEIC ACID SEQUENCING | Singular Genomics Systems, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |
| US-20220136048-A1 | METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES | FIRST-CITIZENS BANK & TRUST COMPANY | 2022-05-05 | — | — | US | disclosed |
| WO-2022094415-A1 | METHODS AND COMPOSITIONS FOR REDUCING NUCLEOTIDE IMPURITIES | Singular Genomics Systems, Inc. (US) | 2022-05-05 | — | — | WO | disclosed |