Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 4/20 | 0.56 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 14/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 13/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 12/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 11/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 7/20 | 0.52 |
| ▸ | USP2 | O75604 | 7/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24399559 | 0.89 | AURKA (0.55) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL25375789 | 0.89 | AURKA (0.55) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL30401990 | 0.89 | AURKA (0.55) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24399745 | 0.87 | AURKA (0.71) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL1460973 | 0.84 | MAPT (0.64) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24399604 | 0.84 | AURKA (0.50) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL29638487 | 0.83 | AURKA (0.49) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL25374488 | 0.83 | AURKA (0.49) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL1460958 | 0.82 | MAPT (0.72) | AURKARPS6KB1MAPTCYP1A2CYP3A4 | |
| SCHEMBL24399556 | 0.81 | AURKA (0.55) | AURKARPS6KB1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |