Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.65 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.59 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4105525 | 0.87 | APLNR (0.69) | APLNRTAS1R3TAS1R1ADRB2ADRB1 | |
| SCHEMBL19138442 | 0.84 | APLNR (0.61) | APLNRTAS1R3TAS1R1LMNATSHR | |
| SCHEMBL19138392 | 0.84 | APLNR (0.61) | APLNRTAS1R3TAS1R1LMNATSHR | |
| SCHEMBL22048877 | 0.84 | APLNR (0.65) | APLNRTAS1R3TAS1R1LMNATSHR | |
| SCHEMBL23460254 | 0.83 | APLNR (0.59) | APLNRTAS1R3TAS1R1TSHRHTR2A | |
| SCHEMBL23460256 | 0.83 | APLNR (0.59) | APLNRTAS1R3TAS1R1TSHRHTR2A | |
| SCHEMBL15969133 | 0.83 | APLNR (0.73) | APLNRTAS1R3TAS1R1ADRB2ADRB1 | |
| SCHEMBL4393397 | 0.83 | APLNR (0.73) | APLNRTAS1R3TAS1R1ADRB2ADRB1 | |
| SCHEMBL7376858 | 0.83 | APLNR (0.73) | APLNRTAS1R3TAS1R1ADRB2ADRB1 | |
| SCHEMBL24999551 | 0.83 | APLNR (0.63) | APLNRTAS1R3TAS1R1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |