Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 10/20 | 0.46 |
| ▸ | BRAF | P15056 | 7/20 | 0.46 |
| ▸ | LCK | P06239 | 3/20 | 0.46 |
| ▸ | TEK | Q02763 | 3/20 | 0.46 |
| ▸ | FLT1 | P17948 | 7/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 4/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | ARAF | P10398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26207944 | 0.84 | KDR (0.46) | KDRBRAFLCKTEKFLT1 | |
| SCHEMBL25376089 | 0.80 | KDR (0.43) | KDRBRAFTEKFLT1FGFR1 | |
| SCHEMBL29123741 | 0.79 | KDR (0.42) | KDRBRAFLCKTEKFLT1 | |
| SCHEMBL24399614 | 0.76 | ADORA2A (0.46) | KDRBRAFLCKTEKFLT1 | |
| SCHEMBL15069866 | 0.75 | BRAF (0.42) | KDRBRAFLCKTEKFLT1 | |
| SCHEMBL29638613 | 0.74 | BRAF (0.61) | BRAFNUDT1RAF1CSF1RDDR1 | |
| SCHEMBL24399766 | 0.74 | BRAF (0.46) | KDRBRAFLCKTEKRAF1 | |
| SCHEMBL2519930 | 0.74 | BRAF (0.77) | KDRBRAFLCKTEKFGFR1 | |
| SCHEMBL15066194 | 0.73 | BRAF (0.78) | KDRBRAFFLT1FGFR1RAF1 | |
| SCHEMBL26209706 | 0.72 | DHODH (0.41) | KDRBRAFFLT1FGFR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022089219-A1 | ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |