SCHEMBL24400289

SCHEMBL24400289

Cc1cc(N)cc([SiH](C)C)c1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.60
TSHR P16473 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.32
ACHE P22303 1/20 0.32
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
C1S P09871 1/20 0.31
PRSS3 P35030 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23027789 0.87 ALDH1A1 (0.42) ALDH1A1TSHRACHEPRSS1PRSS2
SCHEMBL17012261 0.81 ALDH1A1 (0.35) ALDH1A1TSHRACHE
SCHEMBL33318 0.78
SCHEMBL23973980 0.75 ALDH1A1 (0.52) ALDH1A1TSHRNOS3NOS1NOS2
Hydrochloric Acid SCHEMBL2862643 0.74 ALDH1A1 (0.92) ALDH1A1TSHRSMN1; SMN2ACHENOS3
Bromide SCHEMBL22747715 0.74 ALDH1A1 (0.92) ALDH1A1TSHRSMN1; SMN2ACHENOS3
Fluoride SCHEMBL29374673 0.74 ALDH1A1 (0.92) ALDH1A1TSHRSMN1; SMN2ACHENOS3
SCHEMBL178488 0.74
SCHEMBL21611339 0.74 ALDH1A1 (0.92) ALDH1A1TSHRSMN1; SMN2ACHENOS3
Iodide SCHEMBL29022389 0.74 ALDH1A1 (0.92) ALDH1A1TSHRSMN1; SMN2ACHENOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220140274-A1 Light-Emitting Device, Light-Emitting Appliance, Display Device, Electronic Appliance, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-05-05 US disclosed