SCHEMBL23027789

SCHEMBL23027789

Cc1cc(C)cc([SiH](C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 3/20 0.42
ACHE P22303 2/20 0.35
TPMT P51580 1/20 0.33
PRSS1 P07477 1/20 0.32
PRSS2 P07478 1/20 0.32
C1S P09871 1/20 0.32
PRSS3 P35030 1/20 0.32
SELL P14151 1/20 0.32
SELP P16109 1/20 0.32
SELE P16581 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RAPGEF4 Q8WZA2 2/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17012261 0.93 ALDH1A1 (0.35) ALDH1A1TSHRACHESELLSELP
SCHEMBL24400289 0.87 ALDH1A1 (0.60) ALDH1A1TSHRACHEPRSS1PRSS2
SCHEMBL23027839 0.79 RAPGEF4 (0.43) ALDH1A1RAPGEF4
SCHEMBL309146 0.78
SCHEMBL432597 0.78 ALDH1A1 (0.61) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL23027793 0.77
SCHEMBL24400725 0.77 RAPGEF4 (0.41) ALDH1A1RAPGEF4
SCHEMBL16820306 0.76 ALDH1A1 (0.44) ALDH1A1TSHRACHETPMTPRSS1
SCHEMBL3481739 0.75 ALDH1A1 (0.38) ALDH1A1TSHRACHETPMT
SCHEMBL3482235 0.75 ALDH1A1 (0.43) ALDH1A1TSHRACHETPMTPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040492-A Method for synthesizing silanol by catalyzing and oxidizing silane with polyacid 辽宁科技大学 2025-05-27 CN disclosed
CN-115073511-B Green synthesis method for oxidizing silane into silanol 台州学院 2024-09-13 CN disclosed
CN-115073511-A Green synthesis method for oxidizing silane into silanol 台州学院 2022-09-20 CN disclosed
US-20220190246-A1 Light-Emitting Device, Light-Emitting Appliance, Display Device, Electronic Appliance, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-06-16 US disclosed
US-20220140274-A1 Light-Emitting Device, Light-Emitting Appliance, Display Device, Electronic Appliance, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2022-05-05 US disclosed
US-20210057667-A1 LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC APPLIANCE, ORGANIC COMPOUND, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-02-25 US disclosed