Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 20/20 | 0.47 |
| ▸ | HTR2A | P28223 | 19/20 | 0.47 |
| ▸ | HTR2B | P41595 | 6/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18359327 | 0.80 | CYP19A1 (0.33) | — | |
| SCHEMBL19661033 | 0.78 | GRM2 (0.35) | — | |
| SCHEMBL16484167 | 0.75 | GRIN2B (0.36) | — | |
| SCHEMBL24976554 | 0.75 | HTR2A (0.47) | HTR2A | |
| SCHEMBL24976903 | 0.75 | HTR2A (0.47) | HTR2A | |
| SCHEMBL30677346 | 0.75 | IRAK4 (0.33) | — | |
| SCHEMBL20996056 | 0.74 | EGFR (0.33) | — | |
| SCHEMBL19661198 | 0.73 | PDE4B (0.38) | CYP1A2CYP3A4 | |
| SCHEMBL1716185 | 0.73 | TLR7 (0.46) | — | |
| SCHEMBL24400358 | 0.73 | TRPA1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238974-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089454-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |