Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21659932 | 0.84 | TSHR (0.43) | MTNR1AMTNR1BKDM4EKMT2ANPC1 | |
| SCHEMBL21602760 | 0.84 | NOTUM (0.43) | KDM4ENOTUMKMT2ANPC1RAB9A | |
| SCHEMBL26502585 | 0.81 | MTNR1A (0.45) | MTNR1AMTNR1BKDM4EHTTSMN1; SMN2 | |
| SCHEMBL22295793 | 0.81 | MAPT (0.44) | NOTUMRAB9AMAPTHSD17B10TSHR | |
| SCHEMBL20829938 | 0.80 | TSHR (0.47) | KDM4EHTTSMN1; SMN2NOTUMKMT2A | |
| SCHEMBL25016070 | 0.79 | NOTUM (0.58) | KDM4EHTTSMN1; SMN2NOTUMKMT2A | |
| SCHEMBL24455243 | 0.79 | KDM4E (0.57) | KDM4EHTTSMN1; SMN2NOTUMKMT2A | |
| SCHEMBL23571722 | 0.79 | MTNR1A (0.49) | MTNR1AMTNR1BKDM4EHTTSMN1; SMN2 | |
| SCHEMBL25139324 | 0.79 | KDM4E (0.59) | KDM4EHTTSMN1; SMN2NOTUMKMT2A | |
| SCHEMBL21659808 | 0.78 | TSHR (0.42) | MTNR1AMTNR1BKDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022093793-A1 | FOLATE RECEPTOR TARGETED NANOPARTICLE DRUG CONJUGATES AND USES THEREOF | ELUCIDA ONCOLOGY, INC. (US) | 2022-05-05 | — | — | WO | disclosed |