Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24574306 | 0.99 | KDM4E (0.56) | KDM4EHTTSMN1; SMN2HSD17B3ALDH1A1 | |
| SCHEMBL25139324 | 0.89 | KDM4E (0.59) | KDM4EHTTSMN1; SMN2HSD17B3ALDH1A1 | |
| SCHEMBL27407147 | 0.85 | HSD17B3 (0.56) | KDM4EHTTSMN1; SMN2HSD17B3TSHR | |
| SCHEMBL26076765 | 0.85 | HSD17B3 (0.56) | KDM4EHTTSMN1; SMN2HSD17B3TSHR | |
| SCHEMBL26077004 | 0.80 | HSD17B3 (0.41) | KDM4EHTTSMN1; SMN2HSD17B3TSHR | |
| SCHEMBL22652710 | 0.80 | KDM4E (0.58) | KDM4EHTTSMN1; SMN2HSD17B3ALDH1A1 | |
| SCHEMBL20829938 | 0.80 | TSHR (0.47) | KDM4EHTTSMN1; SMN2HSD17B3ALDH1A1 | |
| SCHEMBL24401170 | 0.79 | MTNR1A (0.50) | KDM4EHTTSMN1; SMN2TSHRNOTUM | |
| SCHEMBL25016070 | 0.78 | NOTUM (0.58) | KDM4EHTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL22102183 | 0.77 | HSD17B3 (0.71) | KDM4EHTTSMN1; SMN2HSD17B3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022108452-A1 | TYROSINE-BASED ANTIBODY CONJUGATES | SYNAFFIX B.V. (NL) | 2022-05-27 | — | — | WO | disclosed |