Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617977 | 1.00 | DPP4 (0.54) | DPP4KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL32665417 | 0.88 | DYRK3 (0.58) | DPP4KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL12874554 | 0.85 | DYRK3 (0.60) | DPP4KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL15365501 | 0.85 | KDM4E (0.65) | DPP4KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL15365361 | 0.84 | PIM1 (0.62) | DPP4KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL5620191 | 0.84 | GRK5 (0.46) | DPP4KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL32665401 | 0.84 | PIM1 (0.62) | DPP4KDM4EHSD17B10ALDH1A1CYP1A2 | |
| SCHEMBL4784567 | 0.83 | BRD4 (0.65) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL16456325 | 0.82 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL937211 | 0.81 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022093919-A1 | INHIBITORS OF EXO1 IN COMBINATION WITH OTHER CANCER DRUGS TO INHIBIT CANCER CELLS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-05 | — | — | WO | disclosed |