Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 2/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.58 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.58 |
| ▸ | CDK2 | P24941 | 2/20 | 0.58 |
| ▸ | CDK9 | P50750 | 2/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.58 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.58 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24401671 | 0.88 | DPP4 (0.54) | LRRK2KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL29617977 | 0.88 | DPP4 (0.54) | LRRK2KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL15365501 | 0.85 | KDM4E (0.65) | DYRK3CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL12874554 | 0.85 | DYRK3 (0.60) | DYRK3CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL4784567 | 0.83 | BRD4 (0.65) | CDK2DYRK1ADYRK1BLRRK2KDM4E | |
| SCHEMBL15365361 | 0.81 | PIM1 (0.62) | CDK2DYRK1ALRRK2KDM4EALDH1A1 | |
| SCHEMBL5620191 | 0.81 | GRK5 (0.46) | DYRK3CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL937211 | 0.81 | KDM4E (0.44) | DYRK3CCNT1CCNA2CDK2CDK9 | |
| SCHEMBL32664904 | 0.81 | CDK2 (0.63) | CCNA2CDK2CDK5DYRK1ACDK5R1 | |
| SCHEMBL32665401 | 0.81 | PIM1 (0.62) | CDK2DYRK1ALRRK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022124-A1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV MINNESOTA (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022124-A1 | THERAPEUTIC COMPOUNDS AND METHODS | NR5A1, CYP17A1, CNR1 | DYRK3 4480/4885CCNT1 435/4885CCNA2 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.