Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11825048 | 0.78 | ATM (0.52) | LMNAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL7336448 | 0.73 | ATM (0.52) | LMNAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL7176512 | 0.72 | ATM (0.62) | LMNAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10081124 | 0.72 | LMNA (0.63) | LMNAMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL11063982 | 0.71 | LMNA (0.54) | LMNAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL13342773 | 0.71 | MEN1 (0.53) | LMNAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL10641387 | 0.70 | LMNA (0.61) | LMNAALDH1A1HTTATMSMN1; SMN2 | |
| SCHEMBL1171418 | 0.70 | LMNA (0.56) | LMNAMEN1ALDH1A1KMT2AHTT | |
| SCHEMBL2065470 | 0.69 | SMN1; SMN2 (0.59) | LMNAMEN1ALDH1A1KMT2AKDM4E | |
| SCHEMBL21294313 | 0.69 | ACLY (0.41) | LMNAACLYCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090448-A1 | NOVEL ACYLATING REAGENTS | NOVO NORDISK A/S (DK) | 2022-05-05 | — | — | WO | disclosed |