Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | RGS4 | P49798 | 1/20 | 0.30 |
| ▸ | RGS8 | P57771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360801 | 0.85 | SIGMAR1 (0.42) | SIGMAR1GBA1SLC29A1 | |
| SCHEMBL11101427 | 0.79 | MAPT (0.37) | SIGMAR1 | |
| SCHEMBL12828282 | 0.78 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL22360703 | 0.77 | SIGMAR1 (0.37) | SIGMAR1GBA1SLC29A1 | |
| SCHEMBL1070687 | 0.76 | — | — | |
| SCHEMBL25908114 | 0.76 | — | — | |
| SCHEMBL29299988 | 0.76 | — | — | |
| SCHEMBL21218081 | 0.75 | SIGMAR1 (0.34) | SIGMAR1 | |
| SCHEMBL24402000 | 0.74 | AGL (0.36) | SIGMAR1GBA1 | |
| SCHEMBL24401976 | 0.73 | MAP3K12 (0.36) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090481-A1 | SUBSTITUTED 1H-PYRAZOLO[4,3-C]PYRIDINES AND DERIVATIVES AS EGFR INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |