SCHEMBL24402

SCHEMBL24402

COc1cccc(C(=O)Cl)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.71
CES1 P23141 1/20 0.71
PARP1 P09874 1/20 0.67
NPC1 O15118 6/20 0.59
RAB9A P51151 6/20 0.59
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
PRSS1 P07477 1/20 0.56
PRSS2 P07478 1/20 0.56
PRSS3 P35030 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
ABCG2 Q9UNQ0 1/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
TSHR P16473 2/20 0.54
NPSR1 Q6W5P4 1/20 0.54
STS P08842 1/20 0.54
CHRM2 P08172 1/20 0.54
CHRM1 P11229 1/20 0.54
CHRM3 P20309 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29626810 1.00 CES2 (0.71) CES2CES1PARP1NPC1RAB9A
Ethane SCHEMBL27287143 0.98 CES2 (0.69) CES2CES1PARP1NPC1RAB9A
SCHEMBL11705211 0.93 CES2 (0.62) CES2CES1PARP1NPC1RAB9A
Toluene SCHEMBL27586995 0.90 CES2 (0.59) CES2CES1PARP1NPC1RAB9A
SCHEMBL16712927 0.89 HSD17B2 (0.60) CES2CES1PARP1NPC1RAB9A
SCHEMBL2156482 0.83 CES2 (1.00) CES2CES1PARP1NPC1RAB9A
SCHEMBL726592 0.83 AKR1C3 (0.62) CES2CES1PARP1NPC1RAB9A
SCHEMBL29610859 0.83 CES2 (1.00) CES2CES1PARP1NPC1RAB9A
SCHEMBL4823687 0.83 CES2 (0.77) CES2CES1PARP1NPC1RAB9A
SCHEMBL31414638 0.83 CES2 (0.77) CES2CES1PARP1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2532 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116284203-B Tanshinone IIA C-1 position esterified derivative and preparation method and application thereof 郑州大学 2025-06-10 CN claimed
CN-115703737-B Hydroxypyridones compound and application thereof as antibiotic sensitizer for overcoming bacterial biomembrane resistance 暨南大学 2024-09-24 CN claimed
CN-116891443-B Isoindol-1-one derivative and preparation method and application thereof 潍坊医学院 2023-12-01 CN claimed
CN-117105897-A HNO donor compound and preparation method thereof 海南大学 2023-11-24 CN claimed
CN-117105826-A HNO-releasable compound and preparation method thereof 海南大学 2023-11-24 CN claimed
CN-116284203-A Tanshinone IIA C-1 position esterified derivative and preparation method and application thereof 郑州大学 2023-06-23 CN claimed
CN-115703737-A Hydroxypyridones compounds and application thereof as antibiotic sensitizer for overcoming drug resistance of bacterial biofilm 暨南大学 2023-02-17 CN claimed
CN-114230495-B Hydrogenated nitrosyl donor and preparation method thereof 海南大学 2023-01-06 CN claimed
CN-109796418-B Phenylalanine derivative containing 4-phenyl-1, 2, 3-triazole and preparation method and application thereof 山东大学 2022-03-25 CN claimed
CN-114230495-A Hydrogenated nitrosyl donor and preparation method thereof 海南大学 2022-03-25 CN claimed
CN-104098524-A 1-m-methoxy benzoyl-3-phenyl-1, 4-dihydro-1,2,4,5-tetrazine and preparation and application thereof UNIV ZHEJIANG TECHNOLOGY 2014-10-15 CN claimed
CN-101671245-B Process for preparing 3-methoxypropiophenone TANG BAOQING 2014-07-09 CN claimed
CN-103497182-A 3,4-dichloro isothiazole derivative containing 4,5-dihydro thiazole alkyd resin and preparation method and application thereof UNIV NANKAI 2014-01-08 CN claimed
CN-103232448-A 4, 5-dihydro thiazole alcoholic ester derivative containing 4-methyl-1, 2, 3-thiadiazole and preparation method and application thereof UNIV NANKAI 2013-08-07 CN claimed
CN-103214474-A 5-methyl-1,2,3-thiadiazole derivatives containing 4,5-dihydrothiazole alcohol acid esters and preparation methods and application thereof UNIV NANKAI 2013-07-24 CN claimed
US-8420815-B1 Anti-cancer agents based on N-acyl-2, 3-dihydro-1H-pyrrolo[2,3-b] quinoline derivatives and a method of making U.S. DEPARTMENT OF ENERGY (US) 2013-04-16 US claimed
CN-101671245-A Process for preparing 3-methoxypropiophenone BAOQING TANG 2010-03-17 CN claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
EP-0440329-A1 S-substituted carbonyl substituted betathioacrylamide biocides and fungicides ROHM AND HAAS COMPANY (US) 1991-08-07 EP claimed