Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.56 |
| ▸ | KMO | O15229 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10933601 | 0.98 | AKR1C3 (0.60) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL1193379 | 0.94 | AKR1C3 (0.72) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL7742691 | 0.92 | PARP10 (0.64) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL727287 | 0.92 | PARP10 (0.64) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL10782197 | 0.92 | AKR1C3 (0.70) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL10496906 | 0.89 | TNKS (0.60) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL11217963 | 0.88 | AKR1C3 (0.54) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL6201657 | 0.88 | AKR1C3 (0.54) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL10496995 | 0.85 | HTT (0.55) | AKR1C3TNKSPARP15PARP14PARP10 | |
| SCHEMBL6202616 | 0.85 | LMNA (0.64) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309655-B2 | Methods for the preparation of a poly(arylene ether) polysiloxane multiblock copolymer, multiblock copolymers produced thereby, and associated compositions and articles | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-11-13 | — | — | US | claimed |
| EP-2516501-A1 | METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER | SABIC Innovative Plastics IP B.V. (NL) | 2012-10-31 | — | — | EP | claimed |
| WO-2011077297-A1 | METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2011-06-30 | — | — | WO | claimed |
| US-20110152471-A1 | METHODS FOR THE PREPARATION OF A POLY(ARYLENE ETHER) POLYSILOXANE MULTIBLOCK COPOLYMER, MULTIBLOCK COPOLYMERS PRODUCED THEREBY, AND ASSOCIATED COMPOSITIONS AND ARTICLES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2011-06-23 | — | — | US | claimed |
| JP-2010511095-A | — | — | 2010-04-08 | — | — | JP | claimed |
| US-20080287598-A1 | Method of preparing aramid polymers incorporating carbon nanotubes | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-11-20 | — | — | US | claimed |
| WO-2008066838-A1 | METHOD OF PREPARING ARAMID POLYMERS INCORPORATING CARBON NANOTUBES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-05 | — | — | WO | claimed |
| US-10301430-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2019-05-28 | — | — | US | disclosed |
| US-10294255-B1 | Multifunctional crosslinking agent, crosslinked polymer, and method of making same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2019-05-21 | — | — | US | disclosed |
| EP-2588656-B1 | POLYAMIDE-POLY(ARYLENE ETHER) FIBER AND METHOD FOR ITS PREPARATION | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2019-01-09 | — | — | EP | disclosed |
| US-10113055-B2 | Article comprising poly(phenylene ether)-polysiloxane copolymer composition | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-10-30 | — | — | US | disclosed |
| US-9896545-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-02-20 | — | — | US | disclosed |
| US-20180022872-A1 | BIS(AZOBENZENE) DIAMINES AND PHOTOMECHANICAL POLYMERS MADE THEREFROM | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2018-01-25 | — | — | US | disclosed |
| US-5028372-A | Anisotropic Liquid Solution | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-02 | — | — | US | disclosed |
| US-5001219-A | High modulus poly-p-phenylene terephthalamide fiber | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0348996-A2 | Method and apparatus for producing para-aramid pulp and pulp produced thereby | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-01-03 | — | — | EP | disclosed |
| US-4883634-A | WATER SWELLING, DRYING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4737571-A | REACTING PHENYLENEDIAMINE WITH TEREPHTHALOYL CHLORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| US-4684409-A | SOLUTION POLYMERIZATION OF AROMATIC POLYAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| EP-0229714-A2 | Polymerization of aromatic polyamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301430-B2 | Bis(azobenzene) diamines and photomechanical polymers made therefrom | WASF2, PBRM1, WEE1 | AKR1C3 3702/4885TNKS 775/4885PARP15 457/4885 |
| US-10294255-B1 | Multifunctional crosslinking agent, crosslinked polymer, and method of making same | PARN, PAICS, PAM | AKR1C3 1418/4885TNKS 304/4885PARP15 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.