Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27832635 | 0.85 | IAPP (0.62) | IAPPALOX5APPNPC1POLB | |
| SCHEMBL13287417 | 0.85 | IAPP (0.62) | IAPPALOX5APPNPC1POLB | |
| SCHEMBL2440214 | 0.85 | IAPP (0.62) | IAPPALOX5APPNPC1POLB | |
| SCHEMBL2441249 | 0.85 | IAPP (0.62) | IAPPALOX5APPNPC1POLB | |
| SCHEMBL14205237 | 0.78 | MAOA (0.56) | IAPPALOX5APPNPC1POLB | |
| SCHEMBL19456750 | 0.76 | HDAC1 (0.46) | HDAC4NPC1POLBRAB9AHDAC3 | |
| SCHEMBL3360114 | 0.74 | IAPP (0.58) | IAPPALOX5NPC1POLBRAB9A | |
| SCHEMBL3360109 | 0.74 | IAPP (0.58) | IAPPALOX5NPC1POLBRAB9A | |
| SCHEMBL13287444 | 0.74 | IAPP (0.58) | IAPPALOX5NPC1POLBRAB9A | |
| SCHEMBL27832650 | 0.74 | IAPP (0.58) | IAPPALOX5NPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |