SCHEMBL3360109

SCHEMBL3360109

CCC(=O)/C=C/c1cccc(C)c1.CCC(=O)/C=C/c1cccc(C)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IAPP P10997 3/20 0.58
MAOA P21397 2/20 0.55
MAOB P27338 2/20 0.55
ALOX5 P09917 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
MMP1 P03956 2/20 0.48
MMP2 P08253 2/20 0.48
MMP9 P14780 2/20 0.48
EGFR P00533 1/20 0.48
FBP1 P09467 1/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
POLB P06746 1/20 0.47
XBP1 P17861 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360114 1.00 IAPP (0.58) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL13287444 1.00 IAPP (0.58) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL27832650 1.00 IAPP (0.58) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL14205237 0.88 MAOA (0.56) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL27832635 0.87 IAPP (0.62) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL2441249 0.87 IAPP (0.62) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL2440214 0.87 IAPP (0.62) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL13287417 0.87 IAPP (0.62) IAPPMAOAMAOBALOX5PTGS1
SCHEMBL7057275 0.83 IAPP (0.58) IAPPMAPTKDM4EALDH1A1SMN1; SMN2
SCHEMBL15290066 0.83 IAPP (0.63) IAPPMAOAMAOBMMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137178-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2010-06-03 US claimed
EP-2362765-B1 PERFUME SYSTEMS PROCTER & GAMBLE (US) 2020-04-08 EP disclosed
US-8431520-B2 Perfume systems THE PROCTER & GAMBLE COMPANY (US) 2013-04-30 US disclosed
US-20130012422-A1 PERFUME SYSTEMS SMETS JOHAN (BE) 2013-01-10 US disclosed
US-20100137178-A1 PERFUME SYSTEMS THE PROCTER & GAMBLE COMPANY 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012422-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 IAPP 3778/4885MAOA 45/4885MAOB 160/4885
US-20100137178-A1 PERFUME SYSTEMS TRPA1, PORCN, PLIN5 IAPP 3778/4885MAOA 45/4885MAOB 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.