SCHEMBL24404192

SCHEMBL24404192

C=C(C)Cn1c(=O)[nH]c(=O)n(CC(C)C)c1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
B3GNT2 Q9NY97 1/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
MEN1 O00255 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
KMT2A Q03164 1/20 0.37
APEX1 P27695 1/20 0.36
ADORA2A P29274 1/20 0.35
ADORA2B P29275 1/20 0.35
HTT P42858 1/20 0.35
SIRT1 Q96EB6 1/20 0.34
SIRT3 Q9NTG7 1/20 0.34
SIRT5 Q9NXA8 1/20 0.34
RGS4 P49798 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RGS8 P57771 1/20 0.33
PDE2A O00408 1/20 0.33
PDE1A P54750 1/20 0.33
PDE1B Q01064 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18333371 0.88 APEX1 (0.44) ALDH1A1KDM4EMEN1GAAKMT2A
SCHEMBL11080013 0.86 APEX1 (0.42) ALDH1A1KDM4EMEN1GAAKMT2A
SCHEMBL17537354 0.84 HTT (0.39) ALDH1A1KDM4EMEN1LMNAKMT2A
SCHEMBL17537379 0.84 HTT (0.39) ALDH1A1KDM4EMEN1LMNAKMT2A
SCHEMBL1008027 0.78 CYP3A4 (0.50) ALDH1A1KDM4EMEN1LMNAGAA
SCHEMBL23004641 0.78 RGS4 (0.41) ALDH1A1LMNAADORA2AADORA2BHTT
SCHEMBL18927853 0.74 RGS4 (0.41) ALDH1A1LMNAADORA2AADORA2BHTT
SCHEMBL295471 0.73 HTT (0.46) ALDH1A1MEN1LMNAKMT2AAPEX1
SCHEMBL1247958 0.72 ALDH1A1 (0.37) ALDH1A1KDM4EMEN1GAAKMT2A
SCHEMBL10951033 0.72 APEX1 (0.44) B3GNT2ALDH1A1KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3780226-B1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY MITSUBISHI CHEM CORP (JP) 2022-05-11 EP disclosed