Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24404490 | 0.95 | ADRB2 (0.38) | ADRB2CHRM3HDAC4HDAC6HDAC1 | |
| SCHEMBL19903846 | 0.75 | ADRB2 (0.36) | ADRB2 | |
| SCHEMBL23223709 | 0.69 | ADRB2 (0.39) | ADRB2 | |
| SCHEMBL24404463 | 0.68 | ADRB2 (0.56) | ADRB2CHRM3 | |
| SCHEMBL21573538 | 0.68 | ADRB2 (0.43) | ADRB2 | |
| SCHEMBL22839802 | 0.67 | KDM4E (0.40) | ADRB2CHRM3HDAC1 | |
| SCHEMBL18017350 | 0.65 | ADRB2 (0.55) | ADRB2CHRM3 | |
| SCHEMBL20373657 | 0.64 | ADRB2 (0.40) | ADRB2 | |
| SCHEMBL21573495 | 0.64 | ADRB2 (0.42) | ADRB2HDAC1 | |
| SCHEMBL10210774 | 0.64 | NPC1 (0.64) | HDAC4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256464-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2022-05-11 | — | — | EP | disclosed |