Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21141410 | 0.89 | TSHR (0.35) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19903994 | 0.89 | TSHR (0.35) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19980960 | 0.87 | TSHR (0.34) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18951503 | 0.84 | ALDH1A1 (0.36) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL19904001 | 0.84 | TSHR (0.32) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL22476583 | 0.83 | BRPF1 (0.39) | CYP1A2CYP2D6HTR3AHTR4MEN1 | |
| SCHEMBL19903956 | 0.82 | CYP1A2 (0.31) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18951470 | 0.82 | MEN1 (0.38) | TSHRMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18951571 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL22474172 | 0.80 | NPSR1 (0.43) | SMN1; SMN2TSHRCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3715423-B1 | HIGH WET FAST DISPERSE DYE MIXTURES OF N-[4-(5-FLUORO-2,4-DINITRO-PHENYLAZO)-PHENYL]-AMINE DERIVATIVES AND N-[4-(4-NITRO-PHENYLAZO)-PHENYL]-AMINE DERIVATIVES | DYSTAR COLOURS DISTRIB GMBH (DE) | 2022-05-11 | — | — | EP | disclosed |