Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24405919 | 0.81 | CYP1A2 (0.47) | RXFP1MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL24405804 | 0.80 | CYP1A2 (0.40) | RXFP1MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL21116903 | 0.71 | MEN1 (0.47) | RXFP1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL21116343 | 0.71 | MEN1 (0.52) | RXFP1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL21116340 | 0.68 | PGR (0.46) | L3MBTL1MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL21116339 | 0.68 | PGR (0.46) | L3MBTL1MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL14309662 | 0.68 | TDP2 (0.54) | L3MBTL1MAPTHPGDTP53BRPF1 | |
| SCHEMBL24405600 | 0.68 | RXFP1 (0.47) | RXFP1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL4619699 | 0.67 | BRD4 (0.66) | L3MBTL1MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL30293254 | 0.67 | BRD4 (0.66) | L3MBTL1MAPTKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774739-B1 | FUSED CYCLIC UREA DERIVATIVES AS CRHR2 ANTAGONIST | RAQUALIA PHARMA INC (JP) | 2022-05-11 | — | — | EP | disclosed |