SCHEMBL24407697

SCHEMBL24407697

Cc1cc(I)ccc1Oc1ccc(C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 3/20 0.56
TPMT P51580 2/20 0.48
TTR P02766 2/20 0.48
LPAR1 Q92633 5/20 0.47
LPAR5 Q9H1C0 5/20 0.47
RXRB P28702 2/20 0.45
PARP15 Q460N3 1/20 0.45
PARP10 Q53GL7 1/20 0.45
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
SRD5A2 P31213 1/20 0.44
ALDH1A1 P00352 1/20 0.43
RXRG P48443 1/20 0.42
CA12 O43570 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24407702 0.83 RXRA (0.51) RXRATPMTTTRLPAR1LPAR5
SCHEMBL27150812 0.81 RXRA (0.56) RXRATTRLPAR1LPAR5
SCHEMBL26563282 0.81 RXRA (0.55) RXRATPMTTTRLPAR1LPAR5
SCHEMBL5581310 0.80 RXRA (0.55) RXRATTRLPAR1LPAR5RXRB
SCHEMBL5581740 0.80 SRD5A2 (0.58) RXRATTRLPAR1LPAR5RXRB
SCHEMBL7113044 0.80 NTRK1 (0.46) TTR
SCHEMBL24407814 0.80 ALDH1A1 (0.44) CA1CA2ALDH1A1CA12CA7
SCHEMBL19951345 0.79 FFAR1 (0.57) RXRALPAR1LPAR5RXRBSRD5A2
SCHEMBL5581711 0.79 RXRA (0.53) RXRATTRLPAR1LPAR5RXRB
SCHEMBL10148365 0.79 TTR (0.69) RXRATPMTTTRLPAR1LPAR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146935-A1 CARBOXYLATE, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed