SCHEMBL24408917

SCHEMBL24408917

CCOC(=O)CCc1cc(-c2ccccc2)n(C)n1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.54
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.51
ALOX5 P09917 2/20 0.46
PHGDH O43175 1/20 0.46
PTPN1 P18031 1/20 0.45
PTGS1 P23219 1/20 0.45
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
TSHR P16473 1/20 0.44
GAA P10253 1/20 0.44
HTT P42858 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
GLA P06280 1/20 0.43
FAAH O00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24419766 0.89 NR1H4 (0.50) NR1H4ALDH1A1LMNAALOX5PTGS1
SCHEMBL24425215 0.87 LMNA (0.44) NR1H4ALDH1A1LMNAPTGS1CYP4F2
SCHEMBL5966699 0.87 KDM4E (0.49) NR1H4ALDH1A1LMNAPHGDHNPSR1
SCHEMBL24409337 0.85 LMNA (0.49) NR1H4ALDH1A1LMNAALOX5PTPN1
SCHEMBL24419797 0.84 NR1H4 (0.44) NR1H4ALDH1A1LMNAALOX5CYP4F2
SCHEMBL24409133 0.84 NR1H4 (0.44) NR1H4ALDH1A1LMNAALOX5CYP4F2
SCHEMBL24419429 0.83 ALDH1A1 (0.47) NR1H4ALDH1A1LMNACYP4F2CYP4A11
SCHEMBL24419763 0.82 LMNA (0.45) NR1H4ALDH1A1LMNAALOX5CYP4F2
SCHEMBL24408958 0.81 LMNA (0.48) NR1H4ALDH1A1LMNAALOX5CYP4F2
SCHEMBL24419439 0.81 NR1H4 (0.43) NR1H4ALDH1A1LMNAALOX5CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022096450-A1 USE OF [(1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AND THEIR SALTS AND COMPOSITIONS CONTAINING THEM, FOR REDUCING PHYTOTOXIC EFFECTS OF AGROCHEMICALS, IN PARTICULAR OF HERBICIDES, IN USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO disclosed