SCHEMBL24409170

SCHEMBL24409170

Cn1nc(OCC(=O)O)cc1-c1ccc(Cl)cc1F

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.50
PTGDR2 Q9Y5Y4 12/20 0.46
TDP1 Q9NUW8 2/20 0.41
KMO O15229 2/20 0.41
TSHR P16473 1/20 0.40
CTSA P10619 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24409169 0.88 PTGDR2 (0.38) PKMPTGDR2KMOCTSA
SCHEMBL24425289 0.88 PKM (0.52) PKMPTGDR2KMOTSHRCTSA
SCHEMBL24408942 0.88 PKM (0.49) PKMPTGDR2TDP1TSHR
SCHEMBL24409330 0.86 MAPT (0.42) PTGDR2TDP1TSHRMAPT
SCHEMBL24425298 0.86 PKM (0.47) PKMPTGDR2TDP1TSHRMAPT
SCHEMBL24409015 0.84 PKM (0.53) PKMTSHRMAPT
SCHEMBL24409204 0.83 PKM (0.52) PKMPTGDR2TSHRCTSA
SCHEMBL24409329 0.82 PKM (0.53) PKMPTGDR2TDP1TSHRMAPT
SCHEMBL24408971 0.82 MARS1 (0.48) PTGDR2TDP1KMOTSHR
SCHEMBL27114141 0.81 PKM (0.50) PKMPTGDR2TSHRCTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022096450-A1 USE OF [(1,5-DIPHENYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AND THEIR SALTS AND COMPOSITIONS CONTAINING THEM, FOR REDUCING PHYTOTOXIC EFFECTS OF AGROCHEMICALS, IN PARTICULAR OF HERBICIDES, IN USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO disclosed
WO-2022096448-A1 [(5-PHENYL-5-HETEROARYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2022-05-12 WO disclosed