Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | PDE6A | P16499 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24409692 | 0.86 | CYP1A2 (0.38) | SMN1; SMN2ALDH1A1PDE5APDE6AMAPT | |
| SCHEMBL24409691 | 0.84 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL19968462 | 0.83 | TLR7 (0.46) | ALDH1A1PDE4APDE4DTLR7TLR8 | |
| SCHEMBL19968181 | 0.71 | TLR7 (0.44) | PDE4APDE4DTLR7TLR8PDE4B | |
| SCHEMBL19968526 | 0.69 | TLR7 (0.68) | TLR7TLR8 | |
| SCHEMBL19968461 | 0.68 | TLR7 (0.49) | TLR7TLR8LMNA | |
| SCHEMBL4246129 | 0.67 | TLR7 (0.41) | SMN1; SMN2TLR7GAALMNARAB9A | |
| SCHEMBL22923016 | 0.66 | TLR7 (0.53) | TLR7TLR8 | |
| SCHEMBL5807920 | 0.65 | TLR7 (0.43) | SMN1; SMN2MAPTPOLBTLR7TLR8 | |
| SCHEMBL1486523 | 0.65 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1PDE4APDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144833-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXOSMITHKLINE BIOLOGICALS SA (BE) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144833-A1 | IMIDAZOQUINOLINE DERIVATIVES AND THEIR USE IN THERAPY | MAVS, IRF3, MYD88 | SMN1; SMN2 1753/4885ALDH1A1 3845/4885PDE5A 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.