Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878150 | 0.80 | KDM4E (0.33) | KDM4ETDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL115146 | 0.76 | CA12 (0.43) | KDM4EPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL1343863 | 0.76 | KDM4E (0.52) | KDM4EPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL29565140 | 0.76 | KDM4E (0.52) | KDM4EPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL10430895 | 0.76 | POLB (0.43) | KDM4EPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL5535596 | 0.76 | IDO1 (0.40) | KDM4EPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL3398377 | 0.76 | GAA (0.37) | KDM4EPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL7273614 | 0.76 | TDP1 (0.41) | KDM4ETDP1L3MBTL1MAPTALDH1A1 | |
| SCHEMBL2757856 | 0.74 | MAPT (0.41) | KDM4EPOLBTDP1L3MBTL1MAPT | |
| SCHEMBL29948831 | 0.74 | MAPT (0.41) | KDM4EPOLBTDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074585-A2 | MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY | MIRECA MEDICINES GMBH (DE) | 2024-04-11 | — | — | WO | claimed |
| US-20230242568-A1 | POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | MIRECA MEDICINES GMBH (DE) | 2023-08-03 | — | — | US | claimed |
| CN-115161300-A | Aquilaria sinensis-derived III-type polyketide synthase AsPKS3 and coding gene and application thereof | 中国医学科学院药用植物研究所 | 2022-10-11 | — | — | CN | claimed |
| CN-115011576-A | Aquilaria sinensis-derived III-type polyketide synthase AsPKS5, and coding gene and application thereof | 中国医学科学院药用植物研究所 | 2022-09-06 | — | — | CN | claimed |
| CN-114990084-A | Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and coding gene and application thereof | 中国医学科学院药用植物研究所 | 2022-09-02 | — | — | CN | claimed |
| US-11371938-B2 | Nanomaterial-based bacterial sensors | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-06-28 | — | — | US | claimed |
| US-20210317156-A1 | NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | MIRECA MEDICINES GMBH (DE) | 2021-10-14 | — | — | US | claimed |
| US-11001605-B2 | Cyclic dinucleotides containing benzimidazole, method for the production of same, and use of same to activate stimulator of interferon genes (sting)-dependent signaling pathways | BIOLOG LIFE SCIENCE INSTITUTE GMBH & CO. KG (DE) | 2021-05-11 | — | — | US | claimed |
| US-20200182889-A1 | CHEMILUMINESCENT BIOSENSOR FOR DETECTING COAGULATION FACTORS | LEE JI HOON (US) | 2020-06-11 | — | — | US | claimed |
| US-20200158642-A1 | Nanomaterial-based Bacterial Sensors | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-05-21 | — | — | US | claimed |
| CN-1323209-A | Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase | SCIOS INC (US) | 2001-11-21 | — | — | CN | claimed |
| EP-1107758-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2001-06-20 | — | — | EP | claimed |
| WO-2000075306-A2 | METHOD FOR PRODUCING DOUBLE STRANDED POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2000-12-14 | — | — | WO | claimed |
| WO-2000066605-A2 | POLYNUCLEOTIDES | CYCLOPS GENOME SCIENCES LIMITED (GB) | 2000-11-09 | — | — | WO | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-2000012074-A2 | USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE | SCIOS INC. (US) | 2000-03-09 | — | — | WO | claimed |
| WO-1999042435-A2 | MYXOCHELINES | ANALYTICON AG BIOTECHNOLOGIE PHARMAZIE (DE) | 1999-08-26 | — | — | WO | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| US-4908204-A | Reversibly blocked plasmin, t-PA hybrid fibrinolytic enzymes and pharmaceutical compositions and anti-thrombotic use thereof | BEECHAM GROUP P.L.C. (GB) | 1990-03-13 | — | — | US | claimed |
| EP-0155387-B1 | FIBRONOLYTICALLY ACTIVE HYBRID PROTEIN, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITION | BEECHAM GROUP PLC (GB) | 1989-09-06 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230242568-A1 | POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | PRKG1, PRKG2, PRKAG3 | KDM4E 598/4885POLB 1465/4885TDP1 669/4885 |
| US-11001605-B2 | Cyclic dinucleotides containing benzimidazole, method for the production of same, and use of same to activate stimulator of interferon genes (sting)-dependent signaling pathways | STING1, MAVS, CGAS | KDM4E 4243/4885POLB 161/4885TDP1 569/4885 |
| US-20210317156-A1 | NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | PRKG1, PRKG2, PDE7A | KDM4E 638/4885POLB 1528/4885TDP1 690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.