⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20158772 | 1.00 | — | — | |
| SCHEMBL734135 | 1.00 | — | — | |
| SCHEMBL239230 | 0.93 | — | — | |
| SCHEMBL8746924 | 0.93 | — | — | |
| SCHEMBL27176752 | 0.92 | MEN1 (0.35) | — | |
| SCHEMBL23781517 | 0.90 | MEN1 (0.35) | — | |
| SCHEMBL10934751 | 0.87 | MEN1 (0.39) | — | |
| SCHEMBL4921880 | 0.85 | — | — | |
| SCHEMBL10510262 | 0.83 | MEN1 (0.32) | — | |
| SCHEMBL808291 | 0.83 | MEN1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098990-A1 | TARGETED CONJUGATES COMPRISING MODIFIED SIRNA | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-05-12 | — | — | WO | disclosed |
| CN-108884020-A | AMINO ACID AND PEPTIDE CONJUGATES AND CONJUGATION PROCESS | 奥克兰联合服务有限公司 | 2018-11-23 | — | — | CN | disclosed |