SCHEMBL808291

SCHEMBL808291

CCCOC1CCCCO1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
KDM4C Q9H3R0 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.39
ADORA3 P0DMS8 1/20 0.35
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL15743058 0.94 MEN1 (0.40) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL812443 0.94
SCHEMBL8185227 0.94
SCHEMBL18483726 0.89 MEN1 (0.40) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL17324108 0.89 MEN1 (0.40) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL2738489 0.88 MEN1 (0.51) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL4173315 0.88 MEN1 (0.48) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL23691407 0.87 MEN1 (0.45) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL31749262 0.87 MEN1 (0.45) MEN1KMT2AKDM4CNPC1RAB9A
SCHEMBL3379348 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518003-B2 Production process of tetrahydropyran compound and tetrahydropyran compound produced by the production process SHOWA DENKO K.K. (JP) 2009-04-14 US claimed
US-20080139828-A1 Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent SHOWA DENKO K.K. (JP) 2008-06-12 US claimed
EP-1828158-A1 PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS SHOWA DENKO KABUSHIKI KAISHA (JP) 2007-09-05 EP claimed
WO-2006062211-A1 PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS SHOWA DENKO K.K. (JP) 2006-06-15 WO claimed
CN-118184532-A Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same 中外制药株式会社 2024-06-14 CN disclosed
CN-113454058-B Amino acid having functional group capable of forming intramolecular hydrogen bond, peptide compound containing the amino acid, and process for producing the same 中外制药株式会社 2024-03-22 CN disclosed
US-20230399471-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND AND METHOD FOR PRODUCING SURFACE TREATMENT AGENT AGC Inc. (JP) 2023-12-14 US disclosed
US-20230399293-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND AND FLUORINE-CONTAINING COMPOUND AGC Inc. (JP) 2023-12-14 US disclosed
US-20230226002-A1 RETINAL BIOAVAILBILITY OF SYNTHETIC VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS UNIVERSITY OF UTAH RESEARCH FOUNDATION 2023-07-20 US disclosed
WO-2023109878-A1 TRIAZASPIRO LPAR1 ANTAGONIST AND USE THEREOF 武汉人福创新药物研发中心有限公司 2023-06-22 WO disclosed
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-03-30 US disclosed
WO-2022256299-A1 7-MORPHOLINO-5-(3-PHENYL-1 H-PYRAZOL-1 -YL)-FURO[3,2-B]PYRIDINE DERIVATIVES AND SIMILAR COMPOUNDS AS PIKFYVE KINASE INHIBITORS FOR THE TREATMENT OF E.G. AMYOTROPHIC LATERAL SCLEROSIS (ALS) Verge Analytics, Inc. (US) 2022-12-08 WO disclosed
US-20070042152-A1 High-capacity optical storage media CIBA SPECIALTY CHEMICALS CORP. 2007-02-22 US disclosed
US-20070027144-A1 Novel use of cannabinoid receptor agonist SHIONOGI & CO., LTD. (JP) 2007-02-01 US disclosed
WO-2006062211-A1 PRODUCTION PROCESS OF TETRAHYDROPYRAN COMPOUND AND TETRAHYDROPYRAN COMPOUND PRODUCED BY THE PRODUCTION PROCESS SHOWA DENKO K.K. (JP) 2006-06-15 WO disclosed
US-6762170-B1 ANTIINFLAMMATORY AGENTS INHIBIT LEUKOCYTE RECRUITMENT AND ACTIVATION AND ARE AGONISTS OF THE ADENOSINE 2A RECEPTOR; PENDANT ISOXAZOLE; REACTING A 2,6-DIAMINOPURINE WITH A 2-(3-SUBSTITUTED ISOXAZOL-5-YL)TETRAHYDROFURAN-3,4-DIOL SMITHKLINEBEECHAM CORPORATION 2004-07-13 US disclosed
EP-1051425-B1 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES GLAXO GROUP LTD (GB) 2002-10-30 EP disclosed
WO-2001014334-A1 FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY QUESTCOR PHARMACEUTICALS, INC. (US) 2001-03-01 WO disclosed
EP-1051425-A2 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES GLAXO GROUP LIMITED (GB) 2000-11-15 EP disclosed
WO-1999038877-A2 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES GLAXO GROUP LIMITED (GB) 1999-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070027144-A1 Novel use of cannabinoid receptor agonist CNR2, CNR1, OPRM1 MEN1 4737/4885KMT2A 2110/4885KDM4C 2936/4885
US-20230226002-A1 RETINAL BIOAVAILBILITY OF SYNTHETIC VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS ELOVL1, ELOVL3, FFAR2 MEN1 3848/4885KMT2A 3613/4885KDM4C 3982/4885
US-20080139828-A1 Reacting 3,4-dihydro-2-alkoxy-2H-pyran with hydrogen in the presence of a catalyst under acidic condition; Grignard reaction solvent or polymer solvent HPD, ACR, GRHPR MEN1 3558/4885KMT2A 2893/4885KDM4C 3150/4885
US-20230399293-A1 METHOD FOR PRODUCING FLUORINE-CONTAINING COMPOUND AND FLUORINE-CONTAINING COMPOUND AFF1, AFF4, AFF2 MEN1 739/4885KMT2A 74/4885KDM4C 404/4885
US-20230096766-A1 AMINO ACID HAVING FUNCTIONAL GROUP CAPABLE OF INTERMOLECULAR HYDROGEN BONDING, PEPTIDE COMPOUND CONTAINING SAME AND METHOD FOR PRODUCTION THEREOF VIP, DNPEP, HM13 MEN1 1062/4885KMT2A 3453/4885KDM4C 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.