Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.47 |
| ▸ | CDK9 | P50750 | 3/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 5/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21501555 | 0.86 | CDK2 (0.49) | CDK2CDK9CDK5CCNE1CDK5R1 | |
| SCHEMBL6389746 | 0.85 | CDK2 (0.47) | CDK2CDK9CDK5CCNE1CDK5R1 | |
| SCHEMBL6390395 | 0.84 | CDK2 (0.47) | CDK2CDK9CDK5CCNE1CDK5R1 | |
| SCHEMBL5867724 | 0.84 | CDK2 (0.48) | CDK2NLRP3CCNA2CCNA1 | |
| SCHEMBL6387976 | 0.84 | POLB (0.51) | CDK2CDK9CDK5CCNE1CDK5R1 | |
| SCHEMBL5867860 | 0.82 | CDK2 (0.49) | CDK2CDK9CDK5CCNE1CDK5R1 | |
| SCHEMBL6388863 | 0.82 | CDK2 (0.45) | CDK2CDK9CDK5CCNE1CDK5R1 | |
| SCHEMBL5867524 | 0.81 | CDK2 (0.49) | CDK2CDK9CDK5CCNE1CDK5R1 | |
| SCHEMBL5867496 | 0.81 | LMNA (0.50) | CDK2CDK5CCNE1CDK5R1NLRP3 | |
| SCHEMBL5867749 | 0.80 | CDK2 (0.49) | CDK2CDK9CDK5CCNE1CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | NEW YORK UNIVERSITY | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143183-A1 | PHOTOSWITCHABLE PROTACS AND SYNTHESIS AND USES THEREOF | MDM2, UBE3C, CUL1 | CDK2 331/4885CDK9 609/4885CDK5 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.