Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2437798 | 0.93 | ALDH1A1 (0.38) | ALDH1A1MAPTHSD11B1MAOAGAA | |
| SCHEMBL2436030 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPTHSD11B1MAOAGAA | |
| SCHEMBL2438863 | 0.86 | ALDH1A1 (0.37) | ALDH1A1MAPTHSD11B1MAOAACHE | |
| SCHEMBL2437032 | 0.85 | HSD11B1 (0.35) | ALDH1A1MAPTHSD11B1MAOAACHE | |
| SCHEMBL2442275 | 0.83 | ALDH1A1 (0.46) | ALDH1A1MAPTHSD11B1GAATDP1 | |
| Ethane SCHEMBL2436523 | 0.83 | KDM1A (0.36) | ALDH1A1MAPTHSD11B1TDP1NPC1 | |
| Methane SCHEMBL2439045 | 0.83 | KDM1A (0.36) | ALDH1A1MAPTHSD11B1TDP1NPC1 | |
| SCHEMBL2435427 | 0.83 | HSD11B1 (0.34) | ALDH1A1MAPTHSD11B1MAOAGAA | |
| SCHEMBL2437858 | 0.83 | HSD11B1 (0.34) | ALDH1A1MAPTHSD11B1MAOAGAA | |
| SCHEMBL2439602 | 0.81 | KDM1A (0.34) | ALDH1A1MAPTTDP1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2078028-B1 | PHOTOACTIVE COMPOUNDS | AZ ELECTRONIC MATERIALS USA (US) | 2011-09-07 | — | — | EP | claimed |