⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27054784 | 0.89 | RIPK1 (0.30) | — | |
| SCHEMBL25012634 | 0.87 | — | — | |
| SCHEMBL21283626 | 0.86 | — | — | |
| SCHEMBL26210833 | 0.79 | RIPK1 (0.33) | — | |
| SCHEMBL25804278 | 0.78 | — | — | |
| SCHEMBL25519303 | 0.77 | POLRMT (0.30) | — | |
| SCHEMBL25013436 | 0.76 | MEN1 (0.33) | — | |
| SCHEMBL23844017 | 0.76 | RIPK1 (0.32) | — | |
| SCHEMBL23818667 | 0.75 | — | — | |
| SCHEMBL26333107 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230338409-A1 | NUCLEOSIDE DRUGS FOR THE TREATMENT OR PREVENTION OF CORONAVIRUS INFECTION AND THEIR USES | MIRACURE BIOTECHNOLOGY LTD (CN) | 2023-10-26 | — | — | US | disclosed |
| US-20230279015-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20230279013-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2023-09-07 | — | — | US | disclosed |
| US-20230279014-A1 | COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2023-09-07 | — | — | US | disclosed |
| US-11377456-B2 | Crystalline form of Remdesivir | APOTEX INC. (CA) | 2022-07-05 | — | — | US | disclosed |
| US-20220144866-A1 | Crystalline Form of Remdesivir | THE BANK OF NOVA SCOTIA (CA) | 2022-05-12 | — | — | US | disclosed |