SCHEMBL24414756

SCHEMBL24414756

NC1C=CC(C(=O)NCCO)=CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 10/20 0.35
CA1 P00915 10/20 0.35
CA2 P00918 10/20 0.35
CA9 Q16790 10/20 0.35
CA14 Q9ULX7 9/20 0.35
CA3 P07451 9/20 0.35
CA6 P23280 9/20 0.35
CA5A P35218 9/20 0.35
CA7 P43166 9/20 0.35
CA13 Q8N1Q1 9/20 0.35
CA5B Q9Y2D0 9/20 0.35
CA4 P22748 8/20 0.35
CNR2 P34972 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23676905 0.73
SCHEMBL12516760 0.71 MAOB (0.37) KDM4ECYP1A2TSHR
SCHEMBL8215661 0.71 GABRR1 (0.31)
SCHEMBL805476 0.70 GABRR1 (0.37) ALDH1A1KDM4EPOLBHSD17B10L3MBTL1
SCHEMBL24386170 0.70 HTT (0.34) CA12CA1CA2CA9CA14
SCHEMBL24386134 0.68 HTT (0.35) CA12CA1CA2CA9CA14
SCHEMBL19562134 0.67 LMNA (0.38) CA12CA1CA2CA9CA14
SCHEMBL14969753 0.65 BLM (0.33) ALDH1A1KDM4EPOLBHTTL3MBTL1
SCHEMBL8274882 0.65 HDAC3 (0.36)
SCHEMBL24386498 0.63 MMP13 (0.32) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022096673-A1 COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER ITM Isotopen Technologien München AG (DE) 2022-05-12 WO disclosed