Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | F7 | P08709 | 3/20 | 0.44 |
| ▸ | F3 | P13726 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14386822 | 0.93 | MAPK1 (0.48) | MAPK1SLC13A3EGLN1OR51E2MAPT | |
| SCHEMBL21600769 | 0.91 | MAPK1 (0.46) | MAPK1SLC13A3EGLN1OR51E2MAPT | |
| SCHEMBL11678127 | 0.91 | MAPK1 (0.46) | MAPK1SLC13A3EGLN1OR51E2MAPT | |
| SCHEMBL23174677 | 0.91 | MAPK1 (0.46) | MAPK1SLC13A3EGLN1OR51E2MAPT | |
| SCHEMBL28777797 | 0.91 | MAPK1 (0.46) | MAPK1SLC13A3EGLN1OR51E2MAPT | |
| SCHEMBL11676576 | 0.89 | MAPT (0.56) | MAPTABCC4LMNATSHRNFKB1 | |
| SCHEMBL151085 | 0.89 | LMNA (0.61) | EGLN1MAPTABCC4LMNATSHR | |
| SCHEMBL87720 | 0.89 | — | — | |
| SCHEMBL17744969 | 0.86 | LMNA (0.63) | MAPTABCC4LMNATSHRNFKB1 | |
| SCHEMBL258956 | 0.86 | LMNA (0.63) | MAPTABCC4LMNATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2366026-A2 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM ALPHA KETOACIDS | Celexion, Llc (US) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010068944-A2 | BIOLOGICAL SYNTHESIS OF DIFUNCTIONAL ALKANES FROM CARBOHYDRATE FEEDSTOCKS | CELEXION, LLC (US) | 2010-06-17 | — | — | WO | disclosed |