Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 2/20 | 0.38 |
| ▸ | F3 | P13726 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28777797 | 1.00 | MAPK1 (0.46) | MAPK1SLC13A3EGLN1OR51E2TSHR | |
| SCHEMBL23174677 | 1.00 | MAPK1 (0.46) | MAPK1SLC13A3EGLN1OR51E2TSHR | |
| SCHEMBL11678127 | 1.00 | MAPK1 (0.46) | MAPK1SLC13A3EGLN1OR51E2TSHR | |
| SCHEMBL14386822 | 0.98 | MAPK1 (0.48) | MAPK1SLC13A3EGLN1OR51E2TSHR | |
| SCHEMBL2441490 | 0.91 | MAPK1 (0.54) | MAPK1SLC13A3EGLN1OR51E2TSHR | |
| SCHEMBL1296671 | 0.90 | OR51E2 (0.50) | MAPK1SLC13A3EGLN1OR51E2TSHR | |
| Benzene SCHEMBL8775366 | 0.86 | OR51E2 (0.46) | MAPK1SLC13A3EGLN1OR51E2TSHR | |
| SCHEMBL11676576 | 0.84 | MAPT (0.56) | TSHRMAPTABCC4FAAHTERT | |
| SCHEMBL28645746 | 0.83 | CES2 (0.44) | TSHRMAPTABCC4HIF1AFAAH | |
| SCHEMBL10960960 | 0.82 | OR51E2 (0.56) | MAPK1SLC13A3EGLN1OR51E2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019241851-A1 | INHIBITORS OF LYSINE BIOSYNTHESIS VIA THE DIAMINOPIMELATE PATHWAY | LA TROBE UNIVERSITY (AU) | 2019-12-26 | — | — | WO | disclosed |