Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22435470 | 0.79 | ALDH1A1 (0.38) | HSPA5NUDT1KDM4EALDH1A1LMNA | |
| SCHEMBL24415036 | 0.75 | CYP1A2 (0.34) | NUDT1UHRF1HTR1DHTR1B | |
| SCHEMBL26254199 | 0.73 | HSPA5 (0.42) | HSPA5KDM4EALDH1A1LMNAGAA | |
| SCHEMBL22861180 | 0.73 | HSPA5 (0.42) | HSPA5KDM4EALDH1A1LMNAGAA | |
| SCHEMBL14439033 | 0.72 | GRIA1 (0.38) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL9910074 | 0.70 | GRIA1 (0.38) | NUDT1ALDH1A1TDP1UHRF1 | |
| SCHEMBL19678854 | 0.69 | PNMT (0.39) | HSPA5 | |
| SCHEMBL10226464 | 0.67 | KDM4E (0.46) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL4567538 | 0.66 | AR (0.43) | KDM4EALDH1A1LMNATP53GAA | |
| SCHEMBL12942080 | 0.66 | ALDH1A1 (0.36) | NUDT1KDM4EALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144854-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144854-A1 | MACROCYCLIC COMPOUNDS | MCL1, BCL9, CYC1 | HSPA5 4070/4885NUDT1 1999/4885KDM4E 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.