Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 3/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12869178 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDNPSR1NPC1 | |
| SCHEMBL24415299 | 0.81 | MAPT (0.93) | ALDH1A1MAPTHPGDNPSR1NPC1 | |
| SCHEMBL23229431 | 0.81 | MAPT (1.00) | ALDH1A1MAPTHPGDNPSR1NPC1 | |
| SCHEMBL5970126 | 0.80 | MAPT (0.96) | ALDH1A1MAPTHPGDNPSR1NPC1 | |
| SCHEMBL15431904 | 0.78 | ALDH1A1 (0.86) | ALDH1A1MAPTHPGDNPSR1NPC1 | |
| SCHEMBL10724563 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDNPC1SMN1; SMN2 | |
| SCHEMBL12618676 | 0.77 | ALDH1A1 (0.77) | ALDH1A1MAPTHPGDNPC1SMN1; SMN2 | |
| SCHEMBL12618675 | 0.75 | ALDH1A1 (0.67) | ALDH1A1MAPTHPGDNPSR1NPC1 | |
| SCHEMBL19308592 | 0.74 | ALDH1A1 (0.77) | ALDH1A1MAPTHPGDNPSR1NPC1 | |
| SCHEMBL15448164 | 0.74 | ALDH1A1 (0.77) | ALDH1A1MAPTHPGDNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144769-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
| US-20220144759-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144769-A1 | COMPOUND | CBR3, SFXN3, CBR1 | ALDH1A1 928/4885MAPT 4568/4885HPGD 2255/4885 |
| US-20220144759-A1 | COMPOUND | SFXN3, SFXN1, CBR3 | ALDH1A1 1450/4885MAPT 4522/4885HPGD 1584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.