SCHEMBL244157

SCHEMBL244157

OCc1nc2ccccc2s1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
UBE2T Q9NPD8 1/20 0.66
ASIC3 Q9UHC3 1/20 0.66
MAPT P10636 4/20 0.57
SMN1; SMN2 Q16637 6/20 0.56
RAB9A P51151 6/20 0.56
NPC1 O15118 5/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MAPK1 P28482 1/20 0.56
HTT P42858 2/20 0.56
ALOX15 P16050 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C19 P33261 1/20 0.56
KMT2A Q03164 6/20 0.54
MEN1 O00255 4/20 0.54
HPGD P15428 3/20 0.54
ALDH1A1 P00352 2/20 0.54
HSD17B10 Q99714 1/20 0.54
KDM4E B2RXH2 2/20 0.53
GAA P10253 2/20 0.53
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30007395 1.00 UBE2T (0.66) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL3919004 0.84 UBE2T (0.61) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL226465 0.83 UBE2T (0.70) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL19372016 0.83 UBE2T (0.70) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL1903062 0.82 UBE2T (0.54) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL14835424 0.81 SMN1; SMN2 (0.67) UBE2TASIC3MAPTSMN1; SMN2RAB9A
Bromide SCHEMBL7601035 0.81 UBE2T (0.68) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL16397518 0.79 UBE2T (0.66) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL322456 0.79 UBE2T (0.66) UBE2TASIC3MAPTSMN1; SMN2RAB9A
SCHEMBL244156 0.79 UBE2T (0.66) UBE2TASIC3MAPTSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3384066-B1 METHOD FOR MONITORING THE TOTAL AMOUNT OF SULPHUR CONTAINING COMPOUNDS IN A METAL PLATING BATH ATOTECH DEUTSCHLAND GMBH & CO KG (DE) 2023-02-08 EP claimed
CN-115198256-A Reducing solution for electroless copper plating of polyimide film and preparation method and application thereof 上海天承化学有限公司 2022-10-18 CN claimed
EP-3384066-A1 METHOD FOR MONITORING THE TOTAL AMOUNT OF SULPHUR CONTAINING COMPOUNDS IN A METAL PLATING BATH ATOTECH Deutschland GmbH (DE) 2018-10-10 EP claimed
CN-108291304-A Method for monitoring the total amount of sulfur-containing compound in metal plating bath 德国艾托特克公司 2018-07-17 CN claimed
WO-2017093481-A1 METHOD FOR MONITORING THE TOTAL AMOUNT OF SULPHUR CONTAINING COMPOUNDS IN A METAL PLATING BATH ATOTECH DEUTSCHLAND GMBH (DE) 2017-06-08 WO claimed
CN-106632139-A New method for synthesizing benzothiazole-2-formaldehyde and derivative thereof 青岛科技大学 2017-05-10 CN claimed
EP-2970328-B1 NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A ABBVIE DEUTSCHLAND (DE) 2017-04-26 EP claimed
EP-2970328-A1 NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A AbbVie Deutschland GmbH & Co. KG (DE) 2016-01-20 EP claimed
US-9200005-B2 Inhibitor compounds of phosphodiesterase type 10A AbbVie Deutschland GmbH & Co. KG (DE) 2015-12-01 US claimed
US-9139567-B2 Arylpyrazole ethers as inhibitors of leukotriene A4 hydrolase BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-22 US claimed
WO-2013012844-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-01-24 WO claimed
CN-102887973-A Preparation method of white fluorescent powder containing europium terbium beryllium polymer UNIV TAIYUAN TECHNOLOGY 2013-01-23 CN claimed
CN-102827599-A Preparation method of red-green-blue blended white light phosphor UNIV TAIYUAN TECHNOLOGY 2012-12-19 CN claimed
US-7989472-B2 Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use MERCK SHARP & DOHME CORP. (US) 2011-08-02 US claimed
WO-2010138833-A1 SUBSTITUTED IMIDAZO[1,5-a]QUINOXALINES AS INHIBITORS OF PHOSPHODIESTERASE 10 WYETH (US) 2010-12-02 WO claimed
US-20090209564-A1 Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds And Methods Of Use MERCK & CO., INC. 2009-08-20 US claimed
EP-2001472-A2 GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE Merck and Co., Inc. (US) 2008-12-17 EP claimed
WO-2007111864-A2 GLUCAGON RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE MERCK & CO., INC. (US) 2007-10-04 WO claimed
US-5750558-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS ABBOTT LABORATORIES (US) 1998-05-12 US claimed
WO-1997041100-A1 IMINOXY DERIVATIVES OF INDOLE AND INDENE COMPOUNDS AS INHIBITORS OF PROSTAGLANDIN BIOSYNTHESIS ABBOTT LABORATORIES (US) 1997-11-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090209564-A1 Glucagon Receptor Antagonist Compounds, Compositions Containing Such Compounds And Methods Of Use GCGR, GLP1R, GPR119 UBE2T 4126/4885ASIC3 1333/4885MAPT 4554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.