SCHEMBL2441618

SCHEMBL2441618

NCCCC[C@H](NN)C(=O)ON

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.41
GSR P00390 1/20 0.39
RNPEP Q9H4A4 1/20 0.38
CPB2 Q96IY4 6/20 0.38
SIRT6 Q8N6T7 1/20 0.36
SIRT1 Q96EB6 1/20 0.36
GNPAT O15228 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
ANPEP P15144 1/20 0.33
TLR2 O60603 1/20 0.33
SLC6A5 Q9Y345 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7576584 0.85 ANPEP (0.44) FOLH1GSRRNPEPCPB2SIRT6
SCHEMBL6151760 0.85 FOLH1 (0.41) FOLH1GSRRNPEPCPB2SIRT6
SCHEMBL27507131 0.81 FOLH1 (0.46) FOLH1GSRRNPEPCPB2SIRT6
SCHEMBL21412801 0.80 SIRT6 (0.52) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL14178208 0.80 SIRT6 (0.52) FOLH1GSRCPB2SIRT6SIRT1
SCHEMBL27789636 0.80 GSR (0.40) FOLH1GSRRNPEPCPB2SIRT6
SCHEMBL10907791 0.78 ANPEP (0.39) FOLH1CPB2SIRT6SIRT1GNPAT
SCHEMBL12938437 0.78 FOLH1 (0.44) FOLH1GSRRNPEPCPB2SIRT6
SCHEMBL1272606 0.78 FOLH1 (0.58) FOLH1GSRRNPEPCPB2GNPAT
SCHEMBL1272601 0.78 FOLH1 (0.58) FOLH1GSRRNPEPCPB2GNPAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111989339-A Hydrophobic auristatin F compounds and conjugates thereof 西雅图基因公司 2020-11-24 CN claimed
US-11857700-B2 Device with microstructure mediated absorption profile BVW HOLDING AG (CH) 2024-01-02 US disclosed
US-11844875-B2 Microstructured haptotaxic implant BVW HOLDING AG (CH) 2023-12-19 US disclosed
CN-109952118-B Microstructured chemotactic implant BVW控股公司 2022-08-30 CN disclosed
US-20220211905-A1 MICROSTRUCTURED HAPTOTAXIC IMPLANT BVW HOLDING AG (CH) 2022-07-07 US disclosed
US-11331408-B2 Class of anti-adhesion hydrogels with healing aspects BVW HOLDING AG (CH) 2022-05-17 US disclosed
CN-109891021-B Sizing agent for carbon fiber, aqueous dispersion of sizing agent for carbon fiber, and carbon fiber bundle having sizing agent attached thereto 三菱化学株式会社 2022-04-12 CN disclosed
US-20220031734-A1 Medical Device Comprising Boswellic Acid BVW HOLDING AG (CH) 2022-02-03 US disclosed
US-20210290820-A1 MICROSTRUCTURED HAPTOTAXIC IMPLANT BVW HOLDING AG (CH) 2021-09-23 US disclosed
US-11123364-B2 Medical device comprising boswellic acid BVW HOLDING AG (CH) 2021-09-21 US disclosed
CN-103889434-A Medical device comprising boswellic acid BVW HOLDING AG 2014-06-25 CN disclosed
EP-2723357-A1 MEDICAL DEVICE COMPRISING BOSWELLIC ACID BVW Holding AG (CH) 2014-04-30 EP disclosed
WO-2013112381-A2 NEW CLASS OF ANTI-ADHESION HYDROGELS WITH HEALING ASPECTS BVW HOLDING AG (CH) 2013-08-01 WO disclosed
US-20130196003-A1 CLASS OF ANTI-ADHESION HYDROGELS WITH HEALING ASPECTS BVW HOLDING AG (CH) 2013-08-01 US disclosed
WO-2012177825-A1 MEDICAL DEVICE COMPRISING BOSWELLIC ACID BVW HOLDING AG (CH) 2012-12-27 WO disclosed
EP-2367624-A1 USE OF A PISTON REACTOR TO IMPLEMENT A PHOSGENATION PROCESS Perstorp France (FR) 2011-09-28 EP disclosed
WO-2010076515-A1 USE OF A PISTON REACTOR TO IMPLEMENT A PHOSGENATION PROCESS PERSTORP FRANCE (FR) 2010-07-08 WO disclosed
US-20090324489-A1 Wortmannin conjugates and uses thereof BETH ISRAEL DEACONESS MEDICAL CENTER 2009-12-31 US disclosed
EP-1940386-A2 WORTMANNIN CONJUGATES AND USES THEREOF Beth Israel Deaconess Medical Center (US) 2008-07-09 EP disclosed
WO-2007086943-A2 WORTMANNIN CONJUGATES AND USES THEREOF BETH ISRAEL DEACONESS MEDICAL CENTER (US) 2007-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324489-A1 Wortmannin conjugates and uses thereof PIK3CG, PIK3C3, PIK3CA FOLH1 3288/4885GSR 3739/4885RNPEP 4234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.