Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7224727 | 0.85 | ANPEP (0.44) | FOLH1GSRRNPEPCPB2SIRT6 | |
| SCHEMBL7224725 | 0.85 | ANPEP (0.44) | FOLH1GSRRNPEPCPB2SIRT6 | |
| SCHEMBL2441618 | 0.85 | FOLH1 (0.41) | FOLH1GSRRNPEPCPB2SIRT6 | |
| SCHEMBL27507131 | 0.81 | FOLH1 (0.46) | FOLH1GSRRNPEPCPB2SIRT6 | |
| SCHEMBL5271108 | 0.81 | CPB2 (0.54) | FOLH1GSRCPB2SIRT6SIRT1 | |
| SCHEMBL5271116 | 0.81 | CPB2 (0.54) | FOLH1GSRCPB2SIRT6SIRT1 | |
| SCHEMBL21412801 | 0.80 | SIRT6 (0.52) | FOLH1GSRCPB2SIRT6SIRT1 | |
| SCHEMBL9005885 | 0.80 | FOLH1 (0.45) | FOLH1GSRRNPEPCPB2MMP2 | |
| SCHEMBL677964 | 0.80 | SIRT6 (0.39) | FOLH1GSRRNPEPCPB2SIRT6 | |
| SCHEMBL14178208 | 0.80 | SIRT6 (0.52) | FOLH1GSRCPB2SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210338886-A1 | PORT-ACCESSIBLE MULTIDIRECTIONAL REINFORCED MINIMALLY INVASIVE COLLAGEN DEVICE FOR SOFT TISSUE REPAIR | HARBOR MEDTECH, INC. | 2021-11-04 | — | — | US | disclosed |
| US-20200299357-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | HARBOR MEDTECH INC (US) | 2020-09-24 | — | — | US | disclosed |
| US-10611822-B2 | Crosslinked human or animal tissue products and their methods of manufacture and use | HARBOR MEDTECH, INC. (US) | 2020-04-07 | — | — | US | disclosed |
| US-20180207240-A1 | COLLAGEN IV REPLACEMENT | GOLDFINCH BIO, INC. | 2018-07-26 | — | — | US | disclosed |
| US-20170204162-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | HARBOR MEDTECH INC (US) | 2017-07-20 | — | — | US | disclosed |
| EP-3171889-A1 | COLLAGEN IV REPLACEMENT | GOLDFINCH BIOPHARMA, INC. (US) | 2017-05-31 | — | — | EP | disclosed |
| US-9592320-B2 | Crosslinked human or animal tissue products and their methods of manufacture and use | HARBOR MEDTECH, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160303285-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | HARBOR MEDTECH, INC. | 2016-10-20 | — | — | US | disclosed |
| US-9399084-B2 | Crosslinked human or animal tissue products and their methods of manufacture and use | HARBOR MEDTECH, INC. (US) | 2016-07-26 | — | — | US | disclosed |
| US-20160102134-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | HARBOR MEDTECH, INC. | 2016-04-14 | — | — | US | disclosed |
| US-20130030526-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | HARBOR MEDTECH, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-20130029915-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | HARBOR MEDTECH, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| WO-2013016571-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | HARBOR MEDTECH, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
| EP-0898973-B1 | A method of making a crosslinked collagen-based material and bioprosthetic devices produced therefrom | MEDTRONIC INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-0897942-B1 | A method of crosslinking collagen-based material and bioprosthetic devices produced therefrom | MEDTRONIC INC (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20030035786-A1 | Biological tissue adhesives, articles, and methods | MEDTRONIC, INC. | 2003-02-20 | — | — | US | disclosed |
| US-6166184-A | Process for making a bioprosthetic device | MEDTRONIC INC. (US) | 2000-12-26 | — | — | US | disclosed |
| US-6117979-A | MIXING AN EPOXY FUNCTIONALIZED CROSSLINKING AGENT WITH COLLAGEN-BASED MATERIAL IN AQUEOUS MEDIUM AT ACIDIC PH; COLLAGEN CARBOXYL GROUPS REACT WITH AGENT; HEART VALVES WITH GOOD MECHANICAL PROPERTIES, RETAIN FLEXIBILITY | MEDTRONIC, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0898973-A2 | A method of making a crosslinked collagen-based material and bioprosthetic devices produced therefrom | MEDTRONIC, INC. (US) | 1999-03-03 | — | — | EP | disclosed |
| EP-0897942-A1 | A method of crosslinking collagen-based material and bioprosthetic devices produced therefrom | MEDTRONIC, INC. (US) | 1999-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029915-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | COL2A1, COL1A1, COL14A1 | FOLH1 1314/4885GSR 2012/4885RNPEP 596/4885 |
| US-20160102134-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | COL2A1, COL1A1, COL14A1 | FOLH1 1314/4885GSR 2012/4885RNPEP 596/4885 |
| US-10611822-B2 | Crosslinked human or animal tissue products and their methods of manufacture and use | COL2A1, COL1A1, COL14A1 | FOLH1 1314/4885GSR 2012/4885RNPEP 596/4885 |
| US-20170204162-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | COL2A1, COL1A1, COL14A1 | FOLH1 1314/4885GSR 2012/4885RNPEP 596/4885 |
| US-20130030526-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | COL2A1, COL1A1, COL14A1 | FOLH1 1314/4885GSR 2012/4885RNPEP 596/4885 |
| US-20200299357-A1 | CROSSLINKED HUMAN OR ANIMAL TISSUE PRODUCTS AND THEIR METHODS OF MANUFACTURE AND USE | COL2A1, COL1A1, COL14A1 | FOLH1 1314/4885GSR 2012/4885RNPEP 596/4885 |
| US-20030035786-A1 | Biological tissue adhesives, articles, and methods | ICAM1, EPCAM, VCAM1 | FOLH1 1070/4885GSR 4166/4885RNPEP 1011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.