SCHEMBL24416669

SCHEMBL24416669

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1c(-c2ccc(C#N)cc2)c(-n2c3ccc(C)cc3c3cc(C)ccc32)c(-n2c3ccc(C)cc3c3cc(C)ccc32)c(-c2ccc(C#N)cc2)c1-n1c2ccc(C)cc2c2cc(C)ccc21

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
CYP2A6 P11509 1/20 0.44
KIF11 P52732 1/20 0.38
KDM1A O60341 5/20 0.37
GRM2 Q14416 1/20 0.37
CHEK1 O14757 1/20 0.36
EGLN2 Q96KS0 1/20 0.36
AR P10275 1/20 0.36
PADI4 Q9UM07 1/20 0.35
CYP11B2 P19099 3/20 0.35
CYP11B1 P15538 1/20 0.35
MAPKAPK2 P49137 1/20 0.34
PDE9A O76083 1/20 0.34
PDE1C Q14123 1/20 0.34
USP14 P54578 1/20 0.34
CYP19A1 P11511 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21950321 0.86 PDE9A (0.43) ALDH1A1CYP2A6ARPDE9APDE1C
SCHEMBL21950303 0.86 PDE9A (0.43) ALDH1A1CYP2A6ARPDE9APDE1C
SCHEMBL21429537 0.85 KIF11 (0.41) ALDH1A1CYP2A6KIF11KDM1AGRM2
SCHEMBL21950697 0.83 PDE9A (0.43) ALDH1A1CYP2A6ARPDE9APDE1C
SCHEMBL24416681 0.82 KIF11 (0.54) KIF11KDM1ACYP19A1
SCHEMBL24737209 0.82 AR (0.40) ALDH1A1CYP2A6KDM1AGRM2CHEK1
SCHEMBL16127484 0.81 ALDH1A1 (0.38) ALDH1A1CYP2A6USP14
SCHEMBL20061235 0.81 ALDH1A1 (0.38) ALDH1A1CYP2A6USP14CYP19A1
SCHEMBL24416666 0.81 KDM1A (0.40) ALDH1A1KIF11KDM1ACHEK1AR
SCHEMBL21840876 0.81 ALDH1A1 (0.45) ALDH1A1PDE9APDE1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220149281-A1 ORGANIC ELECTROLUMINESCENT DEVICE, DISPLAY PANEL AND DISPLAY DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD (CN) 2022-05-12 US disclosed