Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 18/20 | 0.64 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.64 |
| ▸ | CDK2 | P24941 | 9/20 | 0.62 |
| ▸ | CDK7 | P50613 | 7/20 | 0.62 |
| ▸ | CDK4 | P11802 | 7/20 | 0.62 |
| ▸ | CCND1 | P24385 | 7/20 | 0.62 |
| ▸ | CCNH | P51946 | 6/20 | 0.62 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.62 |
| ▸ | CDK3 | Q00526 | 6/20 | 0.62 |
| ▸ | CDK1 | P06493 | 5/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.62 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.62 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.62 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.62 |
| ▸ | CCNC | P24863 | 2/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.44 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24418662 | 0.90 | CDK9 (0.51) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL24418649 | 0.86 | CCNT1 (0.46) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL24418616 | 0.85 | CCNT1 (0.47) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL29558303 | 0.85 | CDK9 (0.46) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL29558307 | 0.81 | CDK9 (0.43) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL29558095 | 0.81 | CDK9 (0.65) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL29558977 | 0.81 | CDK9 (0.65) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL29558377 | 0.80 | CCNT1 (0.43) | CDK9CCNT1CDK2CDK7CDK4 | |
| SCHEMBL21946429 | 0.78 | CDK9 (1.00) | CDK9CCNT1CDK2CDK7CDK4 | |
| Hydrochloric Acid SCHEMBL29558312 | 0.78 | CDK9 (0.98) | CDK9CCNT1CDK2CDK7CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188084-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | Kronos Bio, Inc. (US) | 2025-06-12 | — | — | US | disclosed |
| EP-4240422-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | Kronos Bio, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022098843-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | Kronos Bio, Inc. (US) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022098843-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | Kronos Bio, Inc. (US) | 2022-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188084-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | CDK9, CDK19, CDKL1 | CDK9 1/4885CCNT1 86/4885CDK2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.