Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447267 | 0.85 | ANPEP (0.77) | ANPEPMEN1KMT2A | |
| SCHEMBL2441866 | 0.72 | ANPEP (0.75) | ANPEPMEN1KMT2A | |
| SCHEMBL16751823 | 0.69 | ANPEP (0.78) | ANPEPMEN1KMT2A | |
| SCHEMBL2443305 | 0.64 | ANPEP (0.63) | ANPEP | |
| SCHEMBL9482297 | 0.62 | HRH3 (0.51) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9480735 | 0.62 | HRH3 (0.46) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9481001 | 0.62 | HRH3 (0.50) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9480625 | 0.62 | ANPEP (0.49) | ANPEPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29578653 | 0.60 | KMT5B (0.71) | MEN1KMT2AKDM4EALDH1A1NSD2 | |
| SCHEMBL1550555 | 0.60 | KMT5B (0.71) | MEN1KMT2AKDM4EALDH1A1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809288-B1 | USE OF 1,4-BIS (3-AMINOALKYL) PIPERAZINE DERIVATIVES IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | INST NAT SANTE RECH MED (FR) | 2011-09-14 | — | — | EP | claimed |